Corresponding Author: Elham Jamali

Co-Authors: Asad MR2, Rassouli A3

Article in press:

Nowadays, due to growth of urbanization, lifestyle is associated with insufficient physical activity. Since physical activity is a key determinant of energy expenditure, thus it is fundamental to energy balance and weight control. Meanwhile, sports science experts are going to design more effective training models such as high-intensity interval training (HIIT) which can be a suitable approach in dealing with cardiovascular problems, obesity, diabetes, etc. On the other hand, resistin is a proinflammatory cytokines found in adipocytes, and some other cells with a particular role in insulin resistance. Therefore, this research based on available data was conducted for the first time to study the effect of HIIT on resistin gene expression in visceral adipose tissue in diet-induced obese male rats. Three groups of rats were used: Control group were fed with standard diet, Fat group with high-fat diet and Training group underwent high-fat diet plus HIIT for 8 weeks. Training included running on a treadmill at 90% of maximum oxygen consumption with 5 repetitions of 30 seconds in each session with one-minute active rest intervals. Then rats were anesthetized and their visceral adipose tissues were sampled and resistin gene expression in tissue samples was measured. This study showed that HIIT could reduce resistin gene expression in the visceral adipose tissue of obese rat. Despite the non-significance difference, resistin gene expression was reduced several folds, so further studies are needed in this field.



Journal name: Internaional Journal of Applied Exercise Physiology


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